Restricted Research - Award List, Note/Discussion Page
Fiscal Year: 2023
294 The University of Texas Rio Grande Valley (142182)
Principal Investigator: Tripathi,Manish Kumar
Total Amount of Contract, Award, or Gift (Annual before 2011): $ 740,000
Exceeds $250,000 (Is it flagged?): Yes
Start and End Dates: 9/1/22 - 7/31/26
Restricted Research: YES
Academic Discipline: Immunology and Microbiology
Department, Center, School, or Institute: Immunology and Microbiology
Title of Contract, Award, or Gift: Role of lncRNA UCA1 in anoikis resistantce and colorectal cancer metastasis
Name of Granting or Contracting Agency/Entity:
U.S. Dept of Health & Human Services
CFDA Link: HHS
93.859
Program Title:
Biomedical Research and Research Training
CFDA Linked: Biomedical Research and Research Training
Note:
SAMs 1.1.1--Colorectal cancer (CRC) is the second deadliest cancer, and patients’ survival rate drops from 90% to 14% when cancer metastasize to the distant organs. Thus, herein, we propose to research the role of a long noncoding RNA (LncRNA) in anoikis resistance, and CRC metastasis. This research study will provide new insights in CRC metastasis and will help in developing innovative therapeutics to improve patients’ survival, generate data for future NIH proposals and training of Hispanic underserved minority students at the University of Texas Rio Grande Valley (UTRGV), which is a major Hispanic serving institution in South Texas Rio Grande Valley region.
Discussion: No discussion notes