Restricted Research - Award List, Note/Discussion Page
Fiscal Year: 2023
357 The University of Texas Rio Grande Valley (142245)
Principal Investigator: Karabulut,Murat
Total Amount of Contract, Award, or Gift (Annual before 2011): $ 1,500
Exceeds $250,000 (Is it flagged?): No
Start and End Dates: 9/22/22 - 7/31/23
Restricted Research: YES
Academic Discipline: Health & Human Performance
Department, Center, School, or Institute: Health & Human Performance
Title of Contract, Award, or Gift: The Effects of Low Volume HIIT vs. MIIT+BFR on Bod
Name of Granting or Contracting Agency/Entity:
Texas Society for Advancement of Health
CFDA: n/a
Program Title: n/a
Note:
SAMs- 1.1.1 This project has an approved IRB. Obesity is associated with accumulated visceral fat and an increased risk of developing cardiovascular diseases (CVDs). Aerobic exercise is a great prescription to induce fat loss and decrease arterial stiffness while improving arterial elasticity. High-intensity interval training (HIIT), by contrast, is a popular anaerobic exercise, and the work intervals do not rely exclusively on oxygen. It involves brief and intense bouts of exercise separated by resting periods, which makes individuals breathe harder and burns more fat than steady state cardio exercise. Thus, individuals with obesity can benefit from HIIT because of its effect on fat burning and time efficiency. Blood flow restriction training (BFR) combined with low- to moderate-intensity aerobic exercise training improves aerobic capacity, muscle hypertrophy, and strength. Therefore, the objective of this research study is to determine the effects of HIIT vs. moderate IIT (MIIT)+BFR on fat loss, hormone concentration, pro-inflammatory cytokine response, and arterial elasticity. Twenty-four male subjects aged 18-40 who are overweight or obese and sedentary or healthy (not known to have any diseases and/or cardiovascular risk factors) will be recruited. Participants in this research study will be randomized into two groups, and each group will perform either the HIIT or MIIT+BFR protocol. The HIIT group will exercise at an intensity of 80-100% Pavg. The MIIT+BFR program involves exercising at an intensity of 40-60% Pavg with continuous BFR at 150-220 mm Hg on the proximal region of both legs. The HIIT vs. MIIT+BFR protocols effects will be compared on the following variables: whole-body fat, regional-body fat, fat-free mass, maximal oxygen consumption (VO2max), arterial elasticity, pulse wave analysis, pulse wave velocity, heart rate (HR), blood pressure (BP), rate of perceived exertion (RPE) and average anaerobic power output. On the first and last training session, saliva samples will be collected in a saliva sample collection kit via passive drool method to determine the salivary hormone and cytokine concentrations of TNF-α and leptin using an enzyme linked immunosorbent assay (ELISA). The data from this research grant will be vital to further develop BFR protocols that can be an alternative training method to reduce the risk of cardiovascular problems, pro-inflammatory cytokines, and improve body composition (i.e., increase muscle mass and fat loss) for individuals with obesity and older adults.
Discussion: No discussion notes