Restricted Research - Award List, Note/Discussion Page
Fiscal Year: 2023
1173 University of Houston (143061)
Principal Investigator: Zastrow,Melissa L
Total Amount of Contract, Award, or Gift (Annual before 2011): $ 813,751
Exceeds $250,000 (Is it flagged?): Yes
Start and End Dates: 2/1/23 - 1/31/28
Restricted Research: YES
Academic Discipline: Chemistry
Department, Center, School, or Institute: Chemistry
Title of Contract, Award, or Gift: CAREER: ELUCIDATING THE ROLES OF EXTRACELLULAR METAL IONS IN GUT MICROBIOTA INTERACTIONS
Name of Granting or Contracting Agency/Entity:
National Science Foundation
CFDA Link: NSF
47.049
Program Title:
n/a
CFDA Linked: Mathematical and Physical Sciences
Note:
The main research objective is to elucidate the fundamental mechanisms for how metals affect cell-cell and cell-host interactions in the gut microbiota. We hypothesize that metals can mediate bacterial nteractions by binding to cell surface molecules and host proteins. Here we will use Lactobacillaceae and a combination of biochemical and analytical methods to establish mechanisms for how metals affect 1) bacterial cell-cell interactions and 2) cell-host interactions between bacteria and mucin proteins. SAMs 1.1.3
Discussion: No discussion notes