Restricted Research - Award List, Note/Discussion Page
Fiscal Year: 2023
1249 University of Houston (143137)
Principal Investigator: Larin,Kirill
Total Amount of Contract, Award, or Gift (Annual before 2011): $ 369,350
Exceeds $250,000 (Is it flagged?): Yes
Start and End Dates: 1/30/23 - 1/29/24
Restricted Research: YES
Academic Discipline: Biomedical Engineering
Department, Center, School, or Institute: Biomedical Engineering
Title of Contract, Award, or Gift: NON-INVASIVE OCT/OCE OF SKIN FIBROSIS IN A BLEO MOUSE MODEL
Name of Granting or Contracting Agency/Entity:
Bristol-Myers Squibb
CFDA: 00.000
Program Title: n/a
Note:
Primary Objective: non-invasive longitudinal skin fibrosis assessment and treatment response assessment using OCT/OCE, in C57BL/6J mice bleo-skin model with test compound, and correlate with biochemical and histological measurements. Exploratory Objective: Determine longitudinal changes in blood biomarkers through Luminex analyses with inflammation and fibrosis panels. Determine the effect of test compound on total hydroxyproline in terminal skin tissues at week 4 SAMs 1.1.1
Discussion: No discussion notes