Restricted Research - Award List, Note/Discussion Page
Fiscal Year: 2023
1773 The University of Texas at El Paso (143661)
Principal Investigator: Al-Hilal,Taslim A
Total Amount of Contract, Award, or Gift (Annual before 2011): $ 1,507,750
Exceeds $250,000 (Is it flagged?): Yes
Start and End Dates: 7/5/22 - 5/31/26
Restricted Research: YES
Academic Discipline: Pharmaceutical Science
Department, Center, School, or Institute: Pharmaceutical Science
Title of Contract, Award, or Gift: Priming pancreatic ductal adenocarcinoma using blood thinners to sensitize the efficacy of checkpoint immunotherapy
Name of Granting or Contracting Agency/Entity:
NIH - NATL INST OF GEN MEDICAL SCIENCES
CFDA Link: HHS
93.859
Program Title:
Biomedical Research and Research Training
CFDA Linked: Biomedical Research and Research Training
Note:
Pancreatic cancers tend to develop small clots, called intratumoral clots, within their vascular network and interstitial milieu. This project will determine the effect of intratumoral fibrin clots on tumor microenvironment and immunity, and whether the use of blood thinners enhance the efficacy of immunotherapy in different subtypes of pancreatic cancer.
Discussion: No discussion notes