Restricted Research - Award List, Note/Discussion Page
Fiscal Year: 2023
1795 The University of Texas at El Paso (143683)
Principal Investigator: Llano,Manuel F
Total Amount of Contract, Award, or Gift (Annual before 2011): $ 615,502
Exceeds $250,000 (Is it flagged?): Yes
Start and End Dates: 5/22/23 - 4/30/27
Restricted Research: YES
Academic Discipline: Biological Sciences
Department, Center, School, or Institute: Biological Sciences
Title of Contract, Award, or Gift: R16: In vivo relevance of the Schlafen-mediated innate immune mechanism in flavivirus infection
Name of Granting or Contracting Agency/Entity:
NIH - NATL INST OF ALLERGY & INFECTIOU D
Program Title: #N/A
Note:
In this application we aim to define, at the molecular level, several aspects of the mechanism of action of SLFN11 and determine the anti-flavivirus activity of other members of the SLFN family, as well as the in vivo relevance of this defense system. Therefore, this investigation is highly relevant and will significantly advance our understanding of the antiviral mechanism of action of SLFN proteins, which is currently unknown.
Discussion: No discussion notes