Restricted Research - Award List, Note/Discussion Page
Fiscal Year: 2023
1801 The University of Texas at El Paso (143689)
Principal Investigator: Serafine,Katherine Marie
Total Amount of Contract, Award, or Gift (Annual before 2011): $ 605,440
Exceeds $250,000 (Is it flagged?): Yes
Start and End Dates: 6/1/23 - 3/31/27
Restricted Research: YES
Academic Discipline: Psychology
Department, Center, School, or Institute: Psychology
Title of Contract, Award, or Gift: The effects of eating a high fat diet on the therapeutic and abuse-related effects of morphine
Name of Granting or Contracting Agency/Entity:
NIH - NATL INST OF GEN MEDICAL SCIENCES
CFDA Link: HHS
93.859
Program Title:
Biomedical Research and Research Training
CFDA Linked: Biomedical Research and Research Training
Note:
Patients diagnosed with obesity are at an increased risk both of being prescribed opioid analgesics (for chronic pain conditions) and developing opioid use disorder; however, the mechanisms that underlie these risks are not well understood. This proposal investigates the impact of eating a high fat diet (which can lead to obesity) on the therapeutic and abuse-related effects of morphine, an opioid analgesic drug, using rat models. These projects will provide a clear picture of the ways that obesity and opioid use disorder converge to increase risk for individuals.
Discussion: No discussion notes