Restricted Research - Award List, Note/Discussion Page
Fiscal Year: 2023
2076 The University of Texas at Dallas (143964)
Principal Investigator: Hoyt,Kenneth Leon
Total Amount of Contract, Award, or Gift (Annual before 2011): $ 2,881,691
Exceeds $250,000 (Is it flagged?): Yes
Start and End Dates: 8/15/22 - 8/15/23
Restricted Research: YES
Academic Discipline: Bioengineering
Department, Center, School, or Institute: ECS
Title of Contract, Award, or Gift: Multifrequency Ultrasound Imaging for Improved Breast Tissue Characterization
Name of Granting or Contracting Agency/Entity:
Natl Institutes of Health
CFDA Link: HHS
93.394
Program Title:
none
CFDA Linked: Cancer Detection and Diagnosis Research
Note:
Our first goal is to implement a multifrequency H-scan ultrasound imaging functionality on programmable scanner equipped with a wideband capacitive micromachined ultrasonic transducer (CMUT). This new ultrasound imaging technology will be tested and optimized using a series of phantom materials embedded with scatterers of known size. Next, we will quantify success of H-scan ultrasound imaging for monitoring an early response to chemotherapy using a preclinical model of breast cancer that recapitulates human disease. We will then compare H-scan ultrasound findings to physical measurements of cancer cell size and results obtained by competing imaging technologies. Lastly, we will conduct the first human study of multifrequency H-scan ultrasound imaging of breast cancer and evaluate the potential for helping with disease management.
Discussion: No discussion notes