Restricted Research - Award List, Note/Discussion Page
Fiscal Year: 2023
2078 The University of Texas at Dallas (143966)
Principal Investigator: Burton,Michael D
Total Amount of Contract, Award, or Gift (Annual before 2011): $ 1,928,001
Exceeds $250,000 (Is it flagged?): Yes
Start and End Dates: 9/1/22 - 7/31/27
Restricted Research: YES
Academic Discipline: Behavioral And Brain Sciences
Department, Center, School, or Institute: BBS
Title of Contract, Award, or Gift: Mechanisms Involved in Postoperative Recovery: A Focus on Pain, Delirium, and Neuroinflammation
Name of Granting or Contracting Agency/Entity:
Natl Institutes of Health
CFDA Link: HHS
93.859
Program Title:
none
CFDA Linked: Biomedical Research and Research Training
Note:
The overarching focus of my research program is to identify neuroimmune mechanisms that contribute to variations in postoperative recovery, such as, pain, cognition, and depression, accounting for age and sex. Our approach will combine innovative technologies and relevant pre-clinical experimental models to investigate monocyte/microglia involvement in postoperative recovery with a focus on pain and delirium. In the past 5 years, we have begun to elucidate how age and sex influences neuroinflammatory processes involved in pain and cognitive deficits to inflammatory stimuli, a condition like surgery. We and others have determined that changes in pain and cognitive states in age is related to “priming” of the immune system and not “current” conditions.
Discussion: No discussion notes