Restricted Research - Award List, Note/Discussion Page
Fiscal Year: 2023
2283 The University of Texas at San Antonio (144171)
Principal Investigator: Hsieh,Jenny
Total Amount of Contract, Award, or Gift (Annual before 2011): $ 2,111,669
Exceeds $250,000 (Is it flagged?): Yes
Start and End Dates: 6/1/19 - 5/31/24
Restricted Research: YES
Academic Discipline: Neurosciences
Department, Center, School, or Institute: COS NEUROSCI DEV & REGEN BIO
Title of Contract, Award, or Gift: Precision models of ARX-associated neurodevelopmental disorders R01NS113516 SCI-8959
Name of Granting or Contracting Agency/Entity:
National Institute of Health
CFDA Link: HHS
93.853
Program Title:
none
CFDA Linked: Extramural Research Programs in the Neurosciences and Neurological Disorders
Note:
SAMS 1.1.1 The two major goals for this research project are to (1) to model common Aristaless-related homeovox (ARX) mutations in mice and human cells to mechanistically understand the basis of these relatively common neurodevelopmental disorders and (2) to more generally understand the mechanism of pathogenesis of polyalanine (pAla) tract expansions, associated with a growing number of human neurodevelopmental disorders.
Discussion: No discussion notes