Restricted Research - Award List, Note/Discussion Page
Fiscal Year: 2023
2337 The University of Texas at San Antonio (144225)
Principal Investigator: Frantz, Douglas
Total Amount of Contract, Award, or Gift (Annual before 2011): $ 383,261
Exceeds $250,000 (Is it flagged?): Yes
Start and End Dates: 9/1/20 - 3/31/23
Restricted Research: YES
Academic Discipline: Sciences
Department, Center, School, or Institute: Chemistry
Title of Contract, Award, or Gift: Optimization of a novel class of microtubule stabilizers
Name of Granting or Contracting Agency/Entity:
University of Texas Health Science Center San Antonio
CFDA Link: HHS
93.395
Program Title:
none
CFDA Linked: Cancer Treatment Research
Note:
SAMs 1.1.1 This collaborative research project will further evaluate whether intrinsic alterations in these signaling pathways are biomarkers of drug response and, reciprocally, follow up on data indicating that the taccas can also alter the functional consequences of these signaling pathways. These studies are significant in that they will lead, in the future, to the generation of a clinical lead candidate for the treatment of drug resistant solid tumors and a greater understanding of their mechanism of action and predictors of response.
Discussion: No discussion notes