Restricted Research - Award List, Note/Discussion Page
Fiscal Year: 2023
2565 The University of Texas at San Antonio (144453)
Principal Investigator: Frantz, Douglas
Total Amount of Contract, Award, or Gift (Annual before 2011): $ 10,000
Exceeds $250,000 (Is it flagged?): No
Start and End Dates: 9/1/22 - 3/31/23
Restricted Research: YES
Academic Discipline: SCIENCES
Department, Center, School, or Institute: Cos Chemistry
Title of Contract, Award, or Gift: Development of highly O-selective Pd-catalyzed alkylation of N/O-containing ambident nucleophiles
Name of Granting or Contracting Agency/Entity:
Bristol-Myers Squibb
CFDA: 0
Program Title: none
Note:
SAMs 1.1.1 I n collaboration with Bristol-Myers Squibb (BMS) team, University will complete optimize Pd catalyst and reaction conditions; assess generality of methodology with various ambident nucleophilic heterocycles (pyridones, uracils, pyrazolols, quinazolinones, diazine N-oxides, etc.); explore substrate scope and limitations; perform kinetic and mechanistic studies.Upon successful completion of the work, a joint publication will be prepared. If a publication is not pursued, a research summary report can be provided
Discussion: No discussion notes